Leveraging disease outbreak news to strengthen the global response to antimicrobial resistance: a call for action

Antimicrobial resistance (AMR) is an escalating global health threat, with low- and middle-income countries (LMICs) bearing the greatest burden as healthcare facilities become breeding grounds for resistant pathogens, leading to increased morbidity, mortality, and straining of already limited resources. The World Health Organization's Disease Outbreak News (DONs) has proven invaluable for early warnings and coordinated responses to infectious disease outbreaks like Ebola and COVID-19, yet AMR events remain largely absent from this system, leading to under-detection, limited global visibility, and ineffective interventions. In this paper, we review the historical evolution of DONs, its supporting frameworks, and the dynamics of AMR outbreaks in LMIC healthcare settings to explore how DONs could be adapted for AMR. We recommend standardizing AMR outbreaks reporting, integrating DONs into response efforts, linking AMR surveillance to DONs workflows, and expanding the definition of Public Health Emergencies of International Concern (PHEIC) to include high-morbidity AMR events, steps that would elevate AMR from a "silent pandemic" to a visible priority.

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Publication Details

Journal
Frontiers in Public Health
Published
2026-01-07
DOI
https://doi.org/10.3389/fpubh.2025.1710596
Primary Topic
Antibiotic Use and Resistance
Type
article
Field-Weighted Citation Impact
0.00

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article

Leveraging disease outbreak news to strengthen the global response to antimicrobial resistance: a call for action

Reuben Kiggundu, Herman Mwanja, Andrew Ddungu Kambugu, Francis Kakooza et al.
Frontiers in Public Health
Antibiotic Use and Resistance
article

Leveraging disease outbreak news to strengthen the global response to antimicrobial resistance: a call for action

Reuben Kiggundu, Herman Mwanja, Andrew Ddungu Kambugu, Francis Kakooza, Dathan M. Byonanebye, David Hope, J. P. Waswa
article en

Abstract

Antimicrobial resistance (AMR) is an escalating global health threat, with low- and middle-income countries (LMICs) bearing the greatest burden as healthcare facilities become breeding grounds for resistant pathogens, leading to increased morbidity, mortality, and straining of already limited resources. The World Health Organization's Disease Outbreak News (DONs) has proven invaluable for early warnings and coordinated responses to infectious disease outbreaks like Ebola and COVID-19, yet AMR events remain largely absent from this system, leading to under-detection, limited global visibility, and ineffective interventions. In this paper, we review the historical evolution of DONs, its supporting frameworks, and the dynamics of AMR outbreaks in LMIC healthcare settings to explore how DONs could be adapted for AMR. We recommend standardizing AMR outbreaks reporting, integrating DONs into response efforts, linking AMR surveillance to DONs workflows, and expanding the definition of Public Health Emergencies of International Concern (PHEIC) to include high-morbidity AMR events, steps that would elevate AMR from a "silent pandemic" to a visible priority.

Frontiers in Public HealthVol. 13
Infectious Diseases Institute (UG), Makerere University (UG)
Wellcome Trust
Openalex Percentile: Top 97%
Antibiotic Use and Resistance
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