Adherence to denosumab therapy and all-cause mortality in dialysis patients with osteoporosis: a retrospective cohort exploratory study

Good adherence to denosumab therapy was associated with lower all-causemortality risk in dialysis patients withosteoporosis. Improving treatment adherence may enhance survival in this high-risk population. Given the exploratory nature of this study and the limited number of events, these findings require validation in larger cohorts.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-01-08
DOI
https://doi.org/10.3389/fphar.2025.1708051
Primary Topic
Parathyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Adherence to denosumab therapy and all-cause mortality in dialysis patients with osteoporosis: a retrospective cohort exploratory study

Chung-Yuan Hsu, Jia-Feng Chen, Ying-Chou Chen, Chien-Hua Chiu et al.
Frontiers in Pharmacology
Parathyroid Disorders and Treatments
article

Adherence to denosumab therapy and all-cause mortality in dialysis patients with osteoporosis: a retrospective cohort exploratory study

Chung-Yuan Hsu, Jia-Feng Chen, Ying-Chou Chen, Chien-Hua Chiu, Shan-Fu Yu
article en

Abstract

Good adherence to denosumab therapy was associated with lower all-causemortality risk in dialysis patients withosteoporosis. Improving treatment adherence may enhance survival in this high-risk population. Given the exploratory nature of this study and the limited number of events, these findings require validation in larger cohorts.

Frontiers in PharmacologyVol. 16
Chang Gung University (TW), Kaohsiung Chang Gung Memorial Hospital (TW)
Chang Gung University, Chang Gung Medical Foundation, Kaohsiung Chang Gung Memorial Hospital
Good health and well-being
Openalex Percentile: Top 97%
Parathyroid Disorders and Treatments
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Adherence to denosumab therapy and all-cause mortality in dialysis patients with osteoporosis: a retrospective cohort exploratory study — Chung-Yuan Hsu, Jia-Feng Chen, et al. · Frontiers in Pharmacology (2026) | TGRS Research Map | TGRS