The NGS and PCR-based Detection of EGFR Mutations in Liquid Biopsy: A Systematic Review and Meta-analysis Compared With Tissue Biopsy in Treatment-naïve Patients With Non-small Cell Lung Cancer
NGS outperforms RT-qPCR in sensitivity and PLR for <i>EGFR</i> mutation detection <i>via</i> LB in patients with NSCLC prior to treatment, reinforcing its potential as a diagnostic tool.
Authors
- Rafael Parra‐Medina (ORCID: https://orcid.org/0000-0002-8428-5837)
- Gabriela Guerron-Gomez
- María Del Socorro Galeano Molina
- Merideidy Plazas Vargas
Institutions
- Instituto Nacional de Cancerología (CO)
- Fundación Universitaria de Ciencias de la Salud (CO)
- Clínica CES (CO)
- Universidad del Rosario (CO)
Publication Details
- Journal
- Cancer Diagnosis & Prognosis
- Published
- 2026-01-03
- DOI
- https://doi.org/10.21873/cdp.10502
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.00