Vanillic Acid Reverses Castor Oil-Induced Diarrhea In BALB/C Mice Through Cholinergic And Calcium Channel Blocking Effects
It reduced intestinal transit stimulated by muscarinic agonist and intestinal secretion induced by PGE<sub>2</sub>. In-vitro experimental results showed vanillic acid's spasmolytic action on jejunum and ileum tissues, likely through VDCC inhibition and muscarinic receptor antagonism.
Authors
- Deeba Bashir
- Abdul Jabbar Shah (ORCID: https://orcid.org/0000-0002-6032-3915)
- Nabi Shah
Institutions
- COMSATS University Islamabad (PK)
Publication Details
- Journal
- Pakistan Journal of Pharmaceutical Sciences
- Published
- 2026-01-07
- DOI
- https://doi.org/10.36721/pjps.2026.39.1.fps.13871.1
- Primary Topic
- Biochemical and biochemical processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00