Spinal epithelioid angiosarcoma: a diagnostically and therapeutically challenging entity treated with chemoradiotherapy

Primary spinal angiosarcoma is extremely rare with few reported cases globally. While en bloc resection is the only definitive and curative treatment modality, this case highlights the potential for curative-intent, non-surgical management of spinal epithelioid angiosarcoma using taxane-based chemoradiotherapy, especially in anatomically challenging and surgically unresectable locations. It also emphasises the role of multimodal imaging and histopathological correlation in the diagnosis and monitoring of rare spinal tumours.

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Publication Details

Journal
BMJ Case Reports
Published
2026-01-01
DOI
https://doi.org/10.1136/bcr-2025-267881
Primary Topic
Vascular Tumors and Angiosarcomas
Type
article
Field-Weighted Citation Impact
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article

Spinal epithelioid angiosarcoma: a diagnostically and therapeutically challenging entity treated with chemoradiotherapy

Ananth Raghuraman, Kawaljit Kaur, Kannan Periasamy, Parthasarathy Vedasoundaram
BMJ Case Reports
Vascular Tumors and Angiosarcomas
article

Spinal epithelioid angiosarcoma: a diagnostically and therapeutically challenging entity treated with chemoradiotherapy

Ananth Raghuraman, Kawaljit Kaur, Kannan Periasamy, Parthasarathy Vedasoundaram
article en

Abstract

Primary spinal angiosarcoma is extremely rare with few reported cases globally. While en bloc resection is the only definitive and curative treatment modality, this case highlights the potential for curative-intent, non-surgical management of spinal epithelioid angiosarcoma using taxane-based chemoradiotherapy, especially in anatomically challenging and surgically unresectable locations. It also emphasises the role of multimodal imaging and histopathological correlation in the diagnosis and monitoring of rare spinal tumours.

BMJ Case ReportsVol. 19(1)
Jawaharlal Institute of Post Graduate Medical Education and Research (IN)
Good health and well-being
Openalex Percentile: Top 97%
Vascular Tumors and Angiosarcomas
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