Evaluation of the anti-hyperglycemic, anti-hyperlipidemic, cardioprotective and anti-inflammatory effects of a xanthine-based dipeptidyl peptidase-4 inhibitor and diosmin in NA/STZ-induced diabetic rats

the findings suggest that linagliptin and diosmin exert strong anti-hyperglycemic, anti-hyperlipidemic, cardioprotective, and anti-inflammatory effects in diabetic rats; the combined treatment effect was the most potent.

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Publication Details

Journal
Archives of Physiology and Biochemistry
Published
2026-01-07
DOI
https://doi.org/10.1080/13813455.2025.2610473
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
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article

Evaluation of the anti-hyperglycemic, anti-hyperlipidemic, cardioprotective and anti-inflammatory effects of a xanthine-based dipeptidyl peptidase-4 inhibitor and diosmin in NA/STZ-induced diabetic rats

Eman Abbas, Asmaa M. El-Kalaawy, Osama M. Ahmed, Noha Abdelazeem Ahmed et al.
Archives of Physiology and Biochemistry
Diabetes Treatment and Management
article

Evaluation of the anti-hyperglycemic, anti-hyperlipidemic, cardioprotective and anti-inflammatory effects of a xanthine-based dipeptidyl peptidase-4 inhibitor and diosmin in NA/STZ-induced diabetic rats

Eman Abbas, Asmaa M. El-Kalaawy, Osama M. Ahmed, Noha Abdelazeem Ahmed, Gamal Eldein F. Abd-Ellatef
article en

Abstract

the findings suggest that linagliptin and diosmin exert strong anti-hyperglycemic, anti-hyperlipidemic, cardioprotective, and anti-inflammatory effects in diabetic rats; the combined treatment effect was the most potent.

Archives of Physiology and Biochemistry
Beni-Suef University (EG), National Research Centre (EG)
Good health and well-being
Openalex Percentile: Top 96%
Diabetes Treatment and Management
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