Mitigating psychological stress-induced cardiac injury: The impact of CB2R agonists on endoplasmic reticulum stress and mitophagy

This study provides mechanistic insight into molecular processes underlying psychological stress-induced cardiac injury. The identified four-gene module may serve as an exploratory molecular signature and a starting point for evaluating CB2R agonism as a modulator of ER stress and mitophagy.

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Publication Details

Journal
Biochemistry and Biophysics Reports
Published
2026-01-06
DOI
https://doi.org/10.1016/j.bbrep.2025.102425
Primary Topic
Endoplasmic Reticulum Stress and Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Mitigating psychological stress-induced cardiac injury: The impact of CB2R agonists on endoplasmic reticulum stress and mitophagy

Cheng Qin, Kan Zhang, Wenbin Gai, Chenke Ma
Biochemistry and Biophysics Reports
Endoplasmic Reticulum Stress and Disease
article

Mitigating psychological stress-induced cardiac injury: The impact of CB2R agonists on endoplasmic reticulum stress and mitophagy

Cheng Qin, Kan Zhang, Wenbin Gai, Chenke Ma
article en

Abstract

This study provides mechanistic insight into molecular processes underlying psychological stress-induced cardiac injury. The identified four-gene module may serve as an exploratory molecular signature and a starting point for evaluating CB2R agonism as a modulator of ER stress and mitophagy.

Biochemistry and Biophysics ReportsVol. 45
Beijing Institute of Education (CN), Chinese PLA General Hospital (CN), Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences, Air Force Medical University (CN)
Good health and well-being
Openalex Percentile: Top 97%
Endoplasmic Reticulum Stress and Disease
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