Non-iatrogenic spinal accessory nerve palsy due to lymph node compression

Injury to the spinal accessory nerve (SAN) is most commonly of iatrogenic or traumatic origin. The incidence of SAN palsy resulting specifically from lymph node compression is difficult to ascertain, as such cases are typically reported in association with malignancies or following surgical procedures. We report the case of an adolescent who presented with clinical features consistent with SAN palsy, including spontaneous shoulder asymmetry, in the absence of prior trauma or surgical intervention to the cervical region. Surgical exploration revealed compression of the SAN by enlarged lymph nodes. Neurolysis of the nerve was performed, resulting in significant clinical improvement. This case is significant for highlighting a rare cause of SAN palsy, adding to the scarce literature on non-iatrogenic origins of the condition.

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Publication Details

Journal
BMJ Case Reports
Published
2026-01-01
DOI
https://doi.org/10.1136/bcr-2025-268594
Primary Topic
Nerve Injury and Rehabilitation
Type
article
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article

Non-iatrogenic spinal accessory nerve palsy due to lymph node compression

Gerardo Millán, Inês Oliveira Pires, Bernardo R. Cavadas, Diogo Casal
BMJ Case Reports
Nerve Injury and Rehabilitation
article

Non-iatrogenic spinal accessory nerve palsy due to lymph node compression

Gerardo Millán, Inês Oliveira Pires, Bernardo R. Cavadas, Diogo Casal
article en

Abstract

Injury to the spinal accessory nerve (SAN) is most commonly of iatrogenic or traumatic origin. The incidence of SAN palsy resulting specifically from lymph node compression is difficult to ascertain, as such cases are typically reported in association with malignancies or following surgical procedures. We report the case of an adolescent who presented with clinical features consistent with SAN palsy, including spontaneous shoulder asymmetry, in the absence of prior trauma or surgical intervention to the cervical region. Surgical exploration revealed compression of the SAN by enlarged lymph nodes. Neurolysis of the nerve was performed, resulting in significant clinical improvement. This case is significant for highlighting a rare cause of SAN palsy, adding to the scarce literature on non-iatrogenic origins of the condition.

BMJ Case ReportsVol. 19(1)
Hospital de São José (PT), Hospital da Luz (PT)
Good health and well-being
Openalex Percentile: Top 97%
Nerve Injury and Rehabilitation
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