Platelet-lymphocyte ratio and its dynamic changes predict mortality in septic acute kidney injury patients: a retrospective multi-center study using U.S. database and Chinese hospital data

Both baseline PLR and its dynamic change during hospitalization may serve as significant predictors of mortality in septic AKI. PLR-based indices could aid in risk stratification and early identification of high-risk patients.

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Publication Details

Journal
PeerJ
Published
2026-01-06
DOI
https://doi.org/10.7717/peerj.20522
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
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article

Platelet-lymphocyte ratio and its dynamic changes predict mortality in septic acute kidney injury patients: a retrospective multi-center study using U.S. database and Chinese hospital data

Mingjing Guan, Xue Xi Tang, Ling Zhang, Caihong Liu et al.
PeerJ
Inflammatory Biomarkers in Disease Prognosis
article

Platelet-lymphocyte ratio and its dynamic changes predict mortality in septic acute kidney injury patients: a retrospective multi-center study using U.S. database and Chinese hospital data

Mingjing Guan, Xue Xi Tang, Ling Zhang, Caihong Liu, Yuliang Zhao, Jinglei Ren, Yongxiu Huang, B Yang, Wei Wei, Ping Fu
article en

Abstract

Both baseline PLR and its dynamic change during hospitalization may serve as significant predictors of mortality in septic AKI. PLR-based indices could aid in risk stratification and early identification of high-risk patients.

PeerJVol. 14
Sichuan University (CN), West China Hospital of Sichuan University (CN)
Good health and well-being
Openalex Percentile: Top 97%
Inflammatory Biomarkers in Disease Prognosis
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