Effectiveness and safety of two‐drug regimens containing an integrase inhibitor and reverse transcriptase inhibitor in a cohort of virologically suppressed people with <scp>HIV</scp> : Data from the <scp>COMBINE</scp> ‐2 study

Among suppressed people living with HIV in a real-world setting, INSTI+RTI two-drug regimens were highly effective and well tolerated over 96 weeks of follow-up.

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Publication Details

Journal
HIV Medicine
Published
2026-01-07
DOI
https://doi.org/10.1111/hiv.70187
Primary Topic
HIV/AIDS drug development and treatment
Type
article
Field-Weighted Citation Impact
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article

Effectiveness and safety of two‐drug regimens containing an integrase inhibitor and reverse transcriptase inhibitor in a cohort of virologically suppressed people with HIV : Data from the COMBINE ‐2 study

Laura Comi, Giorgio Tiecco, Leigh Ragone, A. Pozniak et al.
HIV Medicine
HIV/AIDS drug development and treatment
article

Effectiveness and safety of two‐drug regimens containing an integrase inhibitor and reverse transcriptase inhibitor in a cohort of virologically suppressed people with HIV : Data from the COMBINE ‐2 study

Laura Comi, Giorgio Tiecco, Leigh Ragone, A. Pozniak, Jo Fox, Charlotte Martin, Cassidy Henegar, Frank A. Post, S. De Wit, D. Zucman, Michael Gasser Aboud, Roya Movahedi, L. Assoumou, C Deschanvres, Geoffrey Liegeon, Carl Fletcher, Vani Vannappagari, Jean van Wyk, Chris Kenyon, Margaret Johnson, Jonathan Edwards, Eugenia Quiros Roldan, Cristina Mussini, Marc Delforge, Bryn Jones
article en

Abstract

Among suppressed people living with HIV in a real-world setting, INSTI+RTI two-drug regimens were highly effective and well tolerated over 96 weeks of follow-up.

HIV Medicine
University of Modena and Reggio Emilia (IT), Inserm (FR), King's College London (GB), Guy's and St Thomas' NHS Foundation Trust (GB), The Royal Free Hospital (GB), Forum of European National Highway Research Laboratories (BE), Centre Hospitalier Universitaire de Nantes (FR), Sorbonne Université (FR), ViiV Healthcare (United Kingdom) (GB), Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT), Clinical Research Organization (BD), Ospedale Papa Giovanni XXIII (IT), King's College Hospital NHS Foundation Trust (GB), Hôpital Lariboisière (FR), Institut Pierre Louis d‘Épidémiologie et de Santé Publique (FR), Chelsea and Westminster Hospital (GB), Centre Hospitalier Universitaire de Saint-Pierre (BE), Hôpital Foch (FR), University College London (GB), Instituut voor Tropische Geneeskunde (BE), University of Brescia (IT)
Good health and well-being
Openalex Percentile: Top 97%
HIV/AIDS drug development and treatment
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