Exploring the Potential Link Between Tirzepatide and Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION): Evidence from FAERS and Google Trends

The pharmacovigilance analysis suggests a potential association between tirzepatide and ION, warranting cautious clinical consideration and further investigation. The event is rare but serious. Integrating pharmacovigilance data with digital epidemiology may enhance early signal detection and risk management for rare but clinically significant adverse events such as NAION.

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Publication Details

Journal
Hospital Pharmacy
Published
2026-01-05
DOI
https://doi.org/10.1177/00185787251403040
Primary Topic
Intraoperative Neuromonitoring and Anesthetic Effects
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploring the Potential Link Between Tirzepatide and Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION): Evidence from FAERS and Google Trends

Eleonora Castellana, Maria Rachele Chiappetta
Hospital Pharmacy
Intraoperative Neuromonitoring and Anesthetic Effects
article

Exploring the Potential Link Between Tirzepatide and Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION): Evidence from FAERS and Google Trends

Eleonora Castellana, Maria Rachele Chiappetta
article en

Abstract

The pharmacovigilance analysis suggests a potential association between tirzepatide and ION, warranting cautious clinical consideration and further investigation. The event is rare but serious. Integrating pharmacovigilance data with digital epidemiology may enhance early signal detection and risk management for rare but clinically significant adverse events such as NAION.

Hospital Pharmacy
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
Good health and well-being
Openalex Percentile: Top 97%
Intraoperative Neuromonitoring and Anesthetic Effects
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