Dapagliflozin Reduces Kidney Inflammation in Alport Syndrome by Inhibiting the Stimulator of Interferon Genes Pathway in Renal Tubular Epithelial Cells
Dapagliflozin can reduce proteinuria in patients with Alport syndrome and plays an anti-inflammatory role by inhibiting the STING pathway in tubular epithelial cells of AS mice.
Authors
- Yunzi Liu (ORCID: https://orcid.org/0000-0002-2183-8692)
- Qinjie Weng
- Zhengying Fang
- Pan Xiaoxia
- Hanlan Yu
- Yafei Zhao (ORCID: https://orcid.org/0009-0006-4026-1741)
- Suqin Yu (ORCID: https://orcid.org/0000-0003-3043-4339)
- J Y Xu
- Jingyuan Xie (ORCID: https://orcid.org/0000-0002-5508-0664)
- Y L Jin
- Li Yang
- Qimin Zheng
- Xiangchen Gu
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Yueyang Hospital (CN)
Publication Details
- Journal
- Kidney360
- Published
- 2026-01-07
- DOI
- https://doi.org/10.34067/kid.0000001099
- Primary Topic
- Cell Adhesion Molecules Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00