Diagnostic Potential for IgM Antibody Detection by the DPP Syphilis TnT Assay in Neonates at Risk for Congenital Syphilis

The DPP Syphilis TnT RUO POC assay's treponemal IgM levels discriminated CS risk categories effectively and may supplement current algorithms to improve neonatal CS stratification.

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Publication Details

Journal
medRxiv
Published
2026-01-06
DOI
https://doi.org/10.64898/2026.01.05.26343454
Primary Topic
Syphilis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Diagnostic Potential for IgM Antibody Detection by the DPP Syphilis TnT Assay in Neonates at Risk for Congenital Syphilis

Mark A. Rivieccio, Javan Esfandiari, Dhammika Gunasekera, Konstantin P. Lyashchenko et al.
medRxiv
Syphilis Diagnosis and Treatment
article

Diagnostic Potential for IgM Antibody Detection by the DPP Syphilis TnT Assay in Neonates at Risk for Congenital Syphilis

Mark A. Rivieccio, Javan Esfandiari, Dhammika Gunasekera, Konstantin P. Lyashchenko, Lierni Ugartemendia Ugalde, Irene Stafford, Laura Goetzl, Sabrina DaCosta, AnaLuisa Mosqueda
article en

Abstract

The DPP Syphilis TnT RUO POC assay's treponemal IgM levels discriminated CS risk categories effectively and may supplement current algorithms to improve neonatal CS stratification.

medRxiv
Chembio (United States) (US), The University of Texas Health Science Center (US), The University of Texas Health Science Center at Houston (US)
Bill and Melinda Gates Foundation, University of Texas Health Science Center at Houston, National Institutes of Health
Good health and well-being
Openalex Percentile: Top 97%
Syphilis Diagnosis and Treatment
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