Age-dependent prognostic significance of neutrophil-to-HDL ratio in hepatocellular carcinoma patients
In this cohort of 121 HCC patients, NHR showed a potential association with prognosis in older patients; However, these findings are preliminary due to limited sample size and lack of stratified analyses by disease stage and prior treatment. Future studies should validate these findings in larger, well-characterized cohorts and investigate underlying mechanisms.
Authors
- X. Zhang
- Zhongyi Li (ORCID: https://orcid.org/0000-0001-9365-0325)
- Qingjun Li (ORCID: https://orcid.org/0000-0001-5538-7511)
- Shuaiya Ma (ORCID: https://orcid.org/0000-0001-6089-5246)
- Xiangjun Qian
- Hang Xing (ORCID: https://orcid.org/0000-0002-5634-1037)
- Hao Wang (ORCID: https://orcid.org/0000-0001-7661-3688)
- Feng Han (ORCID: https://orcid.org/0000-0002-9337-7936)
- Ting Wang (ORCID: https://orcid.org/0009-0006-7734-2094)
- Bo Meng
- Hao Zhuang
- Jinxue Zhou
- Yongmei Li
- Zhengzheng Wang
Institutions
- Brown University (US)
- Rhode Island Hospital (US)
- Henan Cancer Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-07
- DOI
- https://doi.org/10.3389/fonc.2025.1620017
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China