Systematic Review and Meta-Analysis of the Clinical Features Associated With Seronegative Autoimmune Encephalitis
Seronegative AE comprises clinically and prognostically distinct subtypes. Early immunotherapy is the key modifiable factor influencing outcome. We advocate for biomarker discovery and prospective, systematically reported cohort studies to improve stratification and treatment strategies in this diagnostically challenging population.
Authors
- Patrick Joseph Waters (ORCID: https://orcid.org/0000-0003-4142-2667)
- Adam E. Handel (ORCID: https://orcid.org/0000-0001-8385-6346)
- Sarosh R. Irani (ORCID: https://orcid.org/0000-0002-7667-9748)
- Victor Mgbachi (ORCID: https://orcid.org/0000-0003-0826-4687)
- Jonathan Cleaver (ORCID: https://orcid.org/0000-0002-9657-5815)
- Sophie Binks (ORCID: https://orcid.org/0000-0003-0991-5998)
- Yihui Goh (ORCID: https://orcid.org/0000-0003-2103-5811)
- Hannah Fox (ORCID: https://orcid.org/0000-0003-4667-4345)
- Nilanka Wickramasinghe
- Thashi Chang
- Smaila Mulic-Al Bunni
- Leonardo Di Cosmo
- Hana Boček
- Justyna Przybysz
- Alessandra Morano
- Soon-Tae Lee
Institutions
- Humanitas University (IT)
- National University of Singapore (SG)
- Charles University (CZ)
- Jacksonville College (US)
- Seoul National University Hospital (KR)
- University of Oxford (GB)
- University Hospital in Motol (CZ)
- Mayo Clinic in Florida (US)
- Oxford University Hospitals NHS Trust (GB)
- National University Health System (SG)
- Sapienza University of Rome (IT)
- University of Colombo (LK)
Publication Details
- Journal
- Neurology Neuroimmunology & Neuroinflammation
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1212/nxi.0000000000200540
- Citations
- 2
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 78.30