Hypertensive disorders of pregnancy and retinopathy of prematurity in extremely preterm infants: A causal mediation analysis
Maternal HDP has a direct protective effect against ROP in extremely preterm infants, whereas fetal growth restriction acts as a pathway that indirectly increases the risk of ROP. The overall effect of HDP on ROP appears to be neutral as these opposing effects offset each other.
Authors
- Kenji Imai (ORCID: https://orcid.org/0000-0002-8163-7083)
- Masahiro Hayakawa (ORCID: https://orcid.org/0000-0001-5217-3219)
- Masahiro Nakatochi (ORCID: https://orcid.org/0000-0002-1838-4837)
- Yumiko Kobayashi (ORCID: https://orcid.org/0000-0002-4578-6743)
- Satoru Katsuki
- Takafumi Ushida
- Yoshiaki Sato (ORCID: https://orcid.org/0000-0001-6320-9176)
- Sho Tano
- Tomomi Kotani
- Seiko Matsuo
- Hiroaki Kajiyama
Institutions
- Hamamatsu University School of Medicine (JP)
- Nagoya University Hospital (JP)
- Japanese Red Cross Nagoya Daini Hospital (JP)
- Kishokai Medical Corporation (JP)
- Nagoya University (JP)
Publication Details
- Journal
- Pregnancy Hypertension
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1016/j.preghy.2025.101410
- Primary Topic
- Retinopathy of Prematurity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00