Analysis of clinical parameters of different types of α-thalassemia children in Hainan region, China
The clinical phenotype of pediatric α-thalassemia is significantly influenced by both genotype and age, with non-deletional Hb H disease presenting the highest risk for systemic complications. These findings emphasize the necessity for genotype-specific monitoring, early nutritional and iron-chelation interventions, and a multidisciplinary follow-up approach to enhance long-term outcomes.
Authors
- Limei Fu
- Zhengnan Sun (ORCID: https://orcid.org/0000-0002-8597-479X)
- Q Li
- Linna Ma
- Fei Sun
- Jinyu Kang
- Yanlin Ma
- Ge Gao
- Yi Gong
- Junhong Chen
- Qiuling Jie
Institutions
- Hainan Modern Women and Children's Hospital (CN)
- Henan Provincial People's Hospital (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2026-01-08
- DOI
- https://doi.org/10.7717/peerj.20586
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00