Insights Into Hereditary Alpha‐Tryptasemia From a Genome‐Wide Association Study in Hymenoptera Venom Anaphylaxis
Summary The G allele in rs111911698 is strongly associated with BST ≥ 8 ng/mL and could serve as a genetic proxy for the detection of HαT in patients with Hymenoptera venom anaphylaxis. The G allele in rs111911698 is a highly sensitive and specific identifier of HαT, with high positive and negative likelihood ratios.
Authors
- Raquel Cruz
- C. Vidal
- Arturo González‐Quintela (ORCID: https://orcid.org/0000-0002-6909-1807)
- Ángel Carracedo
- Mª Ángeles Vargas
- Irene Fernández‐Franco
- Teresa Blanco‐Ramos
Institutions
- Universidade de Santiago de Compostela (ES)
- Complejo Hospitalario Universitario de Santiago (ES)
- Center for Research in Molecular Medicine and Chronic Diseases (ES)
- Fundación Pública Galega de Medicina Xenómica (ES)
Publication Details
- Journal
- Clinical & Experimental Allergy
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1111/cea.70211
- Citations
- 1
- Primary Topic
- Food Allergy and Anaphylaxis Research
- Type
- article
- Field-Weighted Citation Impact
- 34.74
Funders
- Fundación de la Sociedad Española de Alergología e Inmunología Clínica