High-flow nasal cannula oxygenation reduces desaturation risk during diagnostic flexible bronchoscopy under deep sedation: a randomized controlled trial
The application of HFNC can markedly lower the risks of desaturation during FB under deep sedation in a weak flow-dependent manner, while partially mitigating carbon dioxide accumulation, enabling safer deep sedation without intubation.
Authors
- Jennifer Zhang
- Yunfei Cao
- Youhua Wu
- L Wang
- Wanquan Ming
- Yongbin Chen
- Xuefei Zhou (ORCID: https://orcid.org/0000-0003-2978-4315)
- Ming Wang
- Cheng Sheng
- Rong Xu
Institutions
- Ningbo University (CN)
- University of Nottingham Ningbo China (CN)
- Shandong University (CN)
- Ningbo No.6 Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-01-08
- DOI
- https://doi.org/10.3389/fmed.2025.1729660
- Primary Topic
- Airway Management and Intubation Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shandong University
- Zhejiang Medical Association
- Medical and Health Research Project of Zhejiang Province