Clinical outcomes observed with Rivaroxaban versus low molecular weight heparin (Enoxaparin) for thrombo-prophylaxis following total knee arthroplasty: a meta-analysis

Our analysis showed that rivaroxaban when used as thrombo-prophylaxis following TKA, significantly reduced thrombotic outcomes when compared to LMWH. However, the risks of bleeding events including major and minor bleeding events were significantly increased in comparison to LMWH. Therefore, further larger studies should be able to confirm our hypothesis.

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Publication Details

Journal
BMC Cardiovascular Disorders
Published
2026-01-07
DOI
https://doi.org/10.1186/s12872-025-05495-w
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
Field-Weighted Citation Impact
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article

Clinical outcomes observed with Rivaroxaban versus low molecular weight heparin (Enoxaparin) for thrombo-prophylaxis following total knee arthroplasty: a meta-analysis

Yi Peng, Yaxiong Dai, Sha Xia
BMC Cardiovascular Disorders
Venous Thromboembolism Diagnosis and Management
article

Clinical outcomes observed with Rivaroxaban versus low molecular weight heparin (Enoxaparin) for thrombo-prophylaxis following total knee arthroplasty: a meta-analysis

Yi Peng, Yaxiong Dai, Sha Xia
article en

Abstract

Our analysis showed that rivaroxaban when used as thrombo-prophylaxis following TKA, significantly reduced thrombotic outcomes when compared to LMWH. However, the risks of bleeding events including major and minor bleeding events were significantly increased in comparison to LMWH. Therefore, further larger studies should be able to confirm our hypothesis.

BMC Cardiovascular DisordersVol. 26(1)
Huanggang Normal University (CN), Huanggang Central Hospital (CN)
Zero hunger
Openalex Percentile: Top 98%
Venous Thromboembolism Diagnosis and Management
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Clinical outcomes observed with Rivaroxaban versus low molecular weight heparin (Enoxaparin) for thrombo-prophylaxis following total knee arthroplasty: a meta-analysis — Yi Peng, Yaxiong Dai, et al. · BMC Cardiovascular Disorders (2026) | TGRS Research Map | TGRS