Extracorporeal blood purification (HA-380) in rhabdomyolysis-induced acute kidney injury: a successful outcome

Rhabdomyolysis is characterised by muscle breakdown with release of creatine kinase and myoglobin into the bloodstream. Elevated myoglobin levels are a major contributor to acute kidney injury and potentially permanent kidney damage.Conventional renal replacement therapies alone have limited the ability to remove myoglobin due to its molecular size. Timely haemoadsorption may offer a practical solution, enhancing myoglobin clearance and improving outcomes.Prospective studies are needed to establish the optimal use and efficacy of haemoadsorption in rhabdomyolysis-induced acute kidney injury.

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Publication Details

Journal
European Journal of Case Reports in Internal Medicine
Published
2026-01-08
DOI
https://doi.org/10.12890/2026_006059
Primary Topic
Muscle and Compartmental Disorders
Type
article
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article

Extracorporeal blood purification (HA-380) in rhabdomyolysis-induced acute kidney injury: a successful outcome

Ana Paula Beltrán Moschione Castro, Aníbal Sousa Marinho, Marisa Cunha, Sílvia Sousa et al.
European Journal of Case Reports in Internal Medicine
Muscle and Compartmental Disorders
article

Extracorporeal blood purification (HA-380) in rhabdomyolysis-induced acute kidney injury: a successful outcome

Ana Paula Beltrán Moschione Castro, Aníbal Sousa Marinho, Marisa Cunha, Sílvia Sousa, Ricardo Marinho
article en

Abstract

Rhabdomyolysis is characterised by muscle breakdown with release of creatine kinase and myoglobin into the bloodstream. Elevated myoglobin levels are a major contributor to acute kidney injury and potentially permanent kidney damage.Conventional renal replacement therapies alone have limited the ability to remove myoglobin due to its molecular size. Timely haemoadsorption may offer a practical solution, enhancing myoglobin clearance and improving outcomes.Prospective studies are needed to establish the optimal use and efficacy of haemoadsorption in rhabdomyolysis-induced acute kidney injury.

European Journal of Case Reports in Internal MedicineVol. 13(1)
Administração Regional de Saúde de Lisboa e Vale do Tejo (PT), Hospital de Santo António (PT)
Good health and well-being
Openalex Percentile: Top 97%
Muscle and Compartmental Disorders
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