Treating anxiety and depression in people with epilepsy.

The major barriers to detecting, diagnosing and treating depression in the epilepsy clinic are a lack of confidence and a lack of time. Patients with epilepsy have a significantly increased risk of anxiety and depression, and an increased risk of suicide, so conversations about mood should be considered as routine as conversations about SUDEP (sudden unexpected death in epilepsy). Neurologists should feel confident in prescribing serotonin reuptake inhibitors and should know how to refer to local next-stage mental health services if required. Access to psychological well-being services is better than most people are aware of, and self-referral is possible. We would encourage neurologists to strongly consider mental health when prescribing antiseizure medications, especially levetiracetam, and to disseminate such considerations to acute medical, anaesthetic and neurosurgical colleagues. We provide some simple, practical advice to equip neurologists and epilepsy nurses to talk to patients about their mental health and to take initial steps towards treatment.

Authors

Publication Details

Journal
Apollo (University of Cambridge)
Published
2026-01-06
DOI
https://doi.org/10.17863/cam.124483
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
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article

Treating anxiety and depression in people with epilepsy.

Emanuele F. Osimo, Paul C. Fletcher, Thomas Cope
Apollo (University of Cambridge)
Epilepsy research and treatment
article

Treating anxiety and depression in people with epilepsy.

Emanuele F. Osimo, Paul C. Fletcher, Thomas Cope
article en

Abstract

The major barriers to detecting, diagnosing and treating depression in the epilepsy clinic are a lack of confidence and a lack of time. Patients with epilepsy have a significantly increased risk of anxiety and depression, and an increased risk of suicide, so conversations about mood should be considered as routine as conversations about SUDEP (sudden unexpected death in epilepsy). Neurologists should feel confident in prescribing serotonin reuptake inhibitors and should know how to refer to local next-stage mental health services if required. Access to psychological well-being services is better than most people are aware of, and self-referral is possible. We would encourage neurologists to strongly consider mental health when prescribing antiseizure medications, especially levetiracetam, and to disseminate such considerations to acute medical, anaesthetic and neurosurgical colleagues. We provide some simple, practical advice to equip neurologists and epilepsy nurses to talk to patients about their mental health and to take initial steps towards treatment.

Apollo (University of Cambridge)
Good health and well-being
Openalex Percentile: Top 95%
Epilepsy research and treatment
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Treating anxiety and depression in people with epilepsy. — Emanuele F. Osimo, Paul C. Fletcher, et al. · Apollo (University of Cambridge) (2026) | TGRS Research Map | TGRS