Refined pharmacovigilance assessment of immune checkpoint inhibitors-related bullous pemphigoid: a multi-methodological approach utilizing FAERS database
The study establishes a significant link between ICIs and BP. All ICIs increase BP risk. CTLA-4 inhibitors exhibited the most marked early risk concentration, highlighting the importance of early dermatologic evaluation after initiating CTLA-4 blockade.
Authors
- Ya-Gang Zuo
- Liu-yi-yi YANG
- Yan Wang
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Clinical Research Center for Digestive Diseases (CN)
Publication Details
- Journal
- Journal of Pharmacy & Pharmaceutical Sciences
- Published
- 2026-01-07
- DOI
- https://doi.org/10.3389/jpps.2025.15597
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Peking Union Medical College Hospital