Is ER-positive breast cancer a shield against myocardial infarction and its complications? A Mendelian randomization approach
This study provides genetic evidence supporting a protective relationship of causality between ER + BC and Acute MI, as well as MI Complications. The MR analysis suggests that ER + BC may reduce the risk of MI Complications. These findings offer new perspectives for clinical interventions and public health policies.
Authors
- Z. Zhao
- Xiaomin Chen
- Binbin Cao
- Jiahui Li
Institutions
- Ningbo University (CN)
- Ningbo University Affiliated Hospital (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Ningbo First Hospital (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1186/s12872-025-05411-2
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00