The value of the pronucleus size of human single pronucleus zygotes as a predictor of fertility outcomes in conventional in vitro fertilization: a retrospective cohort study
Our results suggest that 1PN zygotes derived from conventional IVF with larger PN diameters have better embryonic development and could be used as predictors of blastocyst formation (> 32.5 μm). However, once the zygotes reach the blastocyst stage, the PN diameter is not associated with pregnancy outcomes.
Authors
- Xueyi Jiang (ORCID: https://orcid.org/0000-0002-5429-1865)
- Danjun Li (ORCID: https://orcid.org/0000-0001-5120-6242)
- Shutian Jiang (ORCID: https://orcid.org/0000-0003-3459-7442)
- Qifeng Lyu (ORCID: https://orcid.org/0000-0002-0012-5781)
- Yan Mi
- Wenzhi Li
Institutions
- Shanghai Ninth People's Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1186/s40001-025-03813-8
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 0.00