Developing a Novel Reference Region for PI‐2620‐PET Imaging to Facilitate Assessment of 4‐Repeat Tauopathies
Our findings strongly suggest temporo-orbital white-matter is superior to inferior cerebellum as a reference region for PI-2620-PET imaging in 4R tauopathies, due to increased sensitivity and purported specificity for 4R tau.
Authors
- Norman Koglin (ORCID: https://orcid.org/0000-0001-7583-8201)
- Gérard N. Bischof (ORCID: https://orcid.org/0000-0002-4366-5171)
- Gábor G. Kovács
- Amir Dehsarvi (ORCID: https://orcid.org/0000-0001-7116-9741)
- Andrew Stephens (ORCID: https://orcid.org/0000-0001-5052-6586)
- Anna Steward (ORCID: https://orcid.org/0000-0002-8438-3760)
- Johannes Levin (ORCID: https://orcid.org/0000-0001-5092-4306)
- Carla Palleis (ORCID: https://orcid.org/0000-0002-4331-8145)
- Johannes Gnörich (ORCID: https://orcid.org/0000-0003-1554-7765)
- Sabrina Katzdobler (ORCID: https://orcid.org/0000-0002-3512-5984)
- Fabian Hirsch (ORCID: https://orcid.org/0000-0002-5370-4031)
- Nicolai Franzmeier (ORCID: https://orcid.org/0000-0001-9736-2283)
- Davina Biel (ORCID: https://orcid.org/0000-0002-2597-1992)
- Mattes Groß
- Sebastian N. Roemer‐Cassiano
- Anna Dewenter
- Lukas Frontzkowski
- Matthias Brendel
- Günter U Höglinger
- Andre Mueller
Institutions
- University Health Network (CA)
- University of Toronto (CA)
- German Center for Neurodegenerative Diseases (DE)
- LMU Klinikum (DE)
- Occupational Cancer Research Centre (CA)
- Munich Cluster for Systems Neurology (DE)
- München Klinik (DE)
- Max Planck Institute for Human Cognitive and Brain Sciences (DE)
- Ludwig-Maximilians-Universität München (DE)
- University of Gothenburg (SE)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_104777
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00