ALPS index and choroid plexus volume as indirect MRI biomarkers of glymphatic function for predicting cognitive decline in Parkinson’s disease
MRI-derived ALPS index and NCPV, while indirect and potentially influenced by multiple factors, were associated with cognitive status and progression in PD. These exploratory markers may aid in identifying individuals at higher risk for cognitive deterioration.
Authors
- T. WANG
- Xinhua Wei
- Xiaofei Huang (ORCID: https://orcid.org/0000-0002-9220-7222)
- Man Li (ORCID: https://orcid.org/0000-0002-4035-5266)
- Shuwen Bu
- Xiuhang Ruan
- Mengfan Wang
- Riyu Guo
- Yuting Li
Institutions
- Guangzhou First People's Hospital (CN)
- First Affiliated Hospital of Jinan University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- NeuroImage
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1016/j.neuroimage.2026.121705
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00