The impact of ceftazidime-avibactam on 30-day mortality in the treatment of OXA-48 producing <i>Enterobacterales</i> infections: a systematic review and meta-analysis

Ceftazidime-avibactam seemed to be associated with a lower 30-day mortality and more favourable clinical outcomes compared with BAT in the treatment of OXA-48 <i>Enterobacterales</i> infections. Although these findings provide tentative support for current ESCMID/IDSA antibiotic use guidelines for the use of ceftazidime-avibactam for OXA-48 <i>Enterobacterales</i> infections, further high-quality research is required to confirm this and evaluate its role in relation with other emerging novel therapies.

Authors

Institutions

Publication Details

Journal
JAC-Antimicrobial Resistance
Published
2025-12-03
DOI
https://doi.org/10.1093/jacamr/dlaf238
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

The impact of ceftazidime-avibactam on 30-day mortality in the treatment of OXA-48 producing Enterobacterales infections: a systematic review and meta-analysis

Shawn Vasoo, Barnaby E Young, Oon Tek Ng, Ashley Li-Ann Foo
JAC-Antimicrobial Resistance
Antibiotic Resistance in Bacteria
article

The impact of ceftazidime-avibactam on 30-day mortality in the treatment of OXA-48 producing Enterobacterales infections: a systematic review and meta-analysis

Shawn Vasoo, Barnaby E Young, Oon Tek Ng, Ashley Li-Ann Foo
article en

Abstract

Ceftazidime-avibactam seemed to be associated with a lower 30-day mortality and more favourable clinical outcomes compared with BAT in the treatment of OXA-48 <i>Enterobacterales</i> infections. Although these findings provide tentative support for current ESCMID/IDSA antibiotic use guidelines for the use of ceftazidime-avibactam for OXA-48 <i>Enterobacterales</i> infections, further high-quality research is required to confirm this and evaluate its role in relation with other emerging novel therapies.

JAC-Antimicrobial ResistanceVol. 8(1)
Nanyang Technological University (SG), Tan Tock Seng Hospital (SG), Public Health Agency (GB), National Centre for Infectious Diseases (SG), National Center for Infectious Diseases (US)
Good health and well-being
Openalex Percentile: Top 44%
Antibiotic Resistance in Bacteria
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.