The impact of ceftazidime-avibactam on 30-day mortality in the treatment of OXA-48 producing <i>Enterobacterales</i> infections: a systematic review and meta-analysis
Ceftazidime-avibactam seemed to be associated with a lower 30-day mortality and more favourable clinical outcomes compared with BAT in the treatment of OXA-48 <i>Enterobacterales</i> infections. Although these findings provide tentative support for current ESCMID/IDSA antibiotic use guidelines for the use of ceftazidime-avibactam for OXA-48 <i>Enterobacterales</i> infections, further high-quality research is required to confirm this and evaluate its role in relation with other emerging novel therapies.
Authors
- Shawn Vasoo (ORCID: https://orcid.org/0000-0001-7812-9881)
- Barnaby E Young
- Oon Tek Ng
- Ashley Li-Ann Foo
Institutions
- Nanyang Technological University (SG)
- Tan Tock Seng Hospital (SG)
- Public Health Agency (GB)
- National Centre for Infectious Diseases (SG)
- National Center for Infectious Diseases (US)
Publication Details
- Journal
- JAC-Antimicrobial Resistance
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1093/jacamr/dlaf238
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00