Robust Performance of Culture, qPCR, and Genomic Approaches for Shigella Serotyping in a Pediatric Surveillance Cohort
All four serotyping methods achieved acceptable accuracy for <i>Shigella</i> vaccine efficacy evaluation. Although discrepancies are infrequent, WGS provides information of their genomic basis.
Authors
- Craig T. Parker (ORCID: https://orcid.org/0000-0002-7719-8882)
- Francesca Schiaffino (ORCID: https://orcid.org/0000-0002-5796-5116)
- Kerry K. Cooper (ORCID: https://orcid.org/0000-0003-4541-1324)
- Patricia B. Pavlinac (ORCID: https://orcid.org/0000-0002-0051-9131)
- Margaret Kosek (ORCID: https://orcid.org/0000-0001-6340-4852)
- Ben Pascoe (ORCID: https://orcid.org/0000-0001-6376-5121)
- Lucero Romaina Cachique
- Pablo Penataro Yori
- Paul F. Garcia Bardales
- Maribel Paredes Olortegui
- Eric Houpt
- Jie Liu
Institutions
- Qingdao University (CN)
- University of Arizona (US)
- Universidad Peruana Cayetano Heredia (PE)
- University of Washington (US)
- University of Oxford (GB)
- Prisma (PE)
- University of Virginia (US)
Publication Details
- Journal
- medRxiv
- Published
- 2026-01-06
- DOI
- https://doi.org/10.64898/2026.01.05.26343460
- Primary Topic
- Escherichia coli research studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bill and Melinda Gates Foundation
- National Institutes of Health