Perfusionist’s role in long-term ventricular assist device

IntroductionVentricular assist devices (VADs) have emerged as essential tools for stage D heart failure, improving survival and quality of life by serving as a bridge to transplant, destination therapy, or bridge to decision. The successful implantation and management of VADs requires a multidisciplinary team, in which perfusionists have a critical role in ensuring proper oxygen delivery, hemodynamic support, and the smooth transition from extracorporeal support to the implanted device. The objective was to describe the institutional perfusion protocol for LVAD implantation and to characterize intraoperative perfusion parameters at a Latin American referral center.MethodsA retrospective observational cohort study was conducted including all patients who underwent LVAD implantation at a referral center in northeastern Colombia. Statistical analysis involved the use of descriptive statistics.ResultsA total of 33 patients underwent LVAD implantation, with a median age of 54 years and 51.52% of male. Ischemic cardiomyopathy was the leading etiology (27.27%). The median cardiopulmonary bypass (CPB) time was 153 min (IQR: 128-181). During cardiopulmonary bypass the median lactate levels were 1.8 mmol/L (IQR: 1.5-2.2), and the cardiac index ranged from a minimum CI of 2.3 to a maximum CI of 2.6 L/min/m<sup>2</sup>.ConclusionsThis study highlights the vital role of cardiopulmonary perfusion in the successful implantation of long-term LVADs in advanced heart failure patients. Optimal intraoperative management, including controlled temperature, low lactate levels, and optimal cardiac index, emphasizes the need for standardized strategies and the expertise of perfusionists.

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Journal
Perfusion
Published
2026-01-05
DOI
https://doi.org/10.1177/02676591251415511
Primary Topic
Mechanical Circulatory Support Devices
Type
article
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article

Perfusionist’s role in long-term ventricular assist device

Maricel Licht-Ardila, Gustavo Prieto, Édgar Fabián Manrique-Hernández, Dafna Garcia Gomez et al.
Perfusion
Mechanical Circulatory Support Devices
article

Perfusionist’s role in long-term ventricular assist device

Maricel Licht-Ardila, Gustavo Prieto, Édgar Fabián Manrique-Hernández, Dafna Garcia Gomez, Alejandra Mendoza-Monsalve, Alexandra Hurtado-Ortiz, Yolly Gigliola Perea Bautista, Leonardo Salazar, Yadira Estrada García
article en

Abstract

IntroductionVentricular assist devices (VADs) have emerged as essential tools for stage D heart failure, improving survival and quality of life by serving as a bridge to transplant, destination therapy, or bridge to decision. The successful implantation and management of VADs requires a multidisciplinary team, in which perfusionists have a critical role in ensuring proper oxygen delivery, hemodynamic support, and the smooth transition from extracorporeal support to the implanted device. The objective was to describe the institutional perfusion protocol for LVAD implantation and to characterize intraoperative perfusion parameters at a Latin American referral center.MethodsA retrospective observational cohort study was conducted including all patients who underwent LVAD implantation at a referral center in northeastern Colombia. Statistical analysis involved the use of descriptive statistics.ResultsA total of 33 patients underwent LVAD implantation, with a median age of 54 years and 51.52% of male. Ischemic cardiomyopathy was the leading etiology (27.27%). The median cardiopulmonary bypass (CPB) time was 153 min (IQR: 128-181). During cardiopulmonary bypass the median lactate levels were 1.8 mmol/L (IQR: 1.5-2.2), and the cardiac index ranged from a minimum CI of 2.3 to a maximum CI of 2.6 L/min/m<sup>2</sup>.ConclusionsThis study highlights the vital role of cardiopulmonary perfusion in the successful implantation of long-term LVADs in advanced heart failure patients. Optimal intraoperative management, including controlled temperature, low lactate levels, and optimal cardiac index, emphasizes the need for standardized strategies and the expertise of perfusionists.

Perfusion
Fundación Cardiovascular de Colombia (CO), Universidad Internacional (MX)
Openalex Percentile: Top 97%
Mechanical Circulatory Support Devices
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