Photobonding of silk fibroin-based hydrogels to rabbit corneas

Silk fibroin-based hydrogels can be successfully bonded to <i>ex vivo</i> rabbit corneas using a sutureless photobonding technique, achieving high bonding strength. The <i>in vivo</i> proof-of-concept study demonstrated the feasibility of the surgical procedure and confirmed corneal re-epithelialization.

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Publication Details

Journal
Frontiers in Bioengineering and Biotechnology
Published
2026-01-05
DOI
https://doi.org/10.3389/fbioe.2025.1739461
Primary Topic
Corneal Surgery and Treatments
Type
article
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article

Photobonding of silk fibroin-based hydrogels to rabbit corneas

Andres De La Hoz, Irene E. Kochevar, Susana Marcos, Rocio Gutierrez-Contreras et al.
Frontiers in Bioengineering and Biotechnology
Corneal Surgery and Treatments
article

Photobonding of silk fibroin-based hydrogels to rabbit corneas

Andres De La Hoz, Irene E. Kochevar, Susana Marcos, Rocio Gutierrez-Contreras, Patricia Gallego-Muñoz, M. Carmen Martínez-García, Mar Fernández-Gutierrez
article en

Abstract

Silk fibroin-based hydrogels can be successfully bonded to <i>ex vivo</i> rabbit corneas using a sutureless photobonding technique, achieving high bonding strength. The <i>in vivo</i> proof-of-concept study demonstrated the feasibility of the surgical procedure and confirmed corneal re-epithelialization.

Frontiers in Bioengineering and BiotechnologyVol. 13
Universidad de Valladolid (ES), Consejo Superior de Investigaciones Científicas (ES), Harvard University (US), Instituto de Óptica "Daza de Valdés" (ES), Massachusetts General Hospital (US), Instituto de Biomedicina y Genética Molecular de Valladolid (ES), University of Rochester (US)
Openalex Percentile: Top 97%
Corneal Surgery and Treatments
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