Denosumab combined with curettage after surgical dislocation of the hip in the treatment of giant cell tumors of bone in the femoral head and neck region: a single-center retrospective study

Denosumab treatment combined with curettage after surgical dislocation of the hip successfully treated GCTB in the femoral head and neck. The safety profile of denosumab as adjuvant therapy was favorable, with no drug-related complications observed. Postoperatively, native hip joints were preserved in all patients, with satisfactory functional outcomes and no evidence of tumor recurrence or metastasis.

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Publication Details

Journal
BMC Musculoskeletal Disorders
Published
2026-01-08
DOI
https://doi.org/10.1186/s12891-025-09451-9
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
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article

Denosumab combined with curettage after surgical dislocation of the hip in the treatment of giant cell tumors of bone in the femoral head and neck region: a single-center retrospective study

Wenfeng Jin, Dongfeng Cai, Jimo Li, Song Hong et al.
BMC Musculoskeletal Disorders
Bone Tumor Diagnosis and Treatments
article

Denosumab combined with curettage after surgical dislocation of the hip in the treatment of giant cell tumors of bone in the femoral head and neck region: a single-center retrospective study

Wenfeng Jin, Dongfeng Cai, Jimo Li, Song Hong, Lvlin Zhao, Zhuobin Yang, Qi Lv, Jing Zhang
article en

Abstract

Denosumab treatment combined with curettage after surgical dislocation of the hip successfully treated GCTB in the femoral head and neck. The safety profile of denosumab as adjuvant therapy was favorable, with no drug-related complications observed. Postoperatively, native hip joints were preserved in all patients, with satisfactory functional outcomes and no evidence of tumor recurrence or metastasis.

BMC Musculoskeletal DisordersVol. 27(1)
Zunyi Medical University (CN), Peking University (CN), Beijing Jishuitan Hospital (CN)
Good health and well-being
Openalex Percentile: Top 97%
Bone Tumor Diagnosis and Treatments
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