Current updates in perioperative care for patients with chronic liver disease
Abstract Patients with chronic liver disease (CLD) are at increased risk of adverse perioperative outcomes. Effective preoperative risk stratification and optimization are critical to minimizing perioperative complications. This article summarizes key aspects of perioperative care in patients with CLD, including pathophysiology, preoperative risk assessment, and evidence-based perioperative care strategies. For patients with hepatocellular carcinoma require liver resection, a multidisciplinary approach is recommended to optimize surgical candidacy and outcomes. In addition, altered bioavailability of opioids and other analgesics necessitates individualized postoperative pain management, emphasizing multimodal approaches tailored to hepatic function. Graphical Abstract
Authors
- Mayura Thilanka Iddagoda (ORCID: https://orcid.org/0000-0002-0631-5797)
- Sherman Picardo (ORCID: https://orcid.org/0000-0001-5013-956X)
- Leon Flicker
Institutions
- The University of Western Australia (AU)
- Royal Perth Hospital (AU)
Publication Details
- Journal
- Anesthesiology and Perioperative Science
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1007/s44254-025-00143-0
- Primary Topic
- Cancer, Stress, Anesthesia, and Immune Response
- Type
- article
- Field-Weighted Citation Impact
- 0.00