Current updates in perioperative care for patients with chronic liver disease

Abstract Patients with chronic liver disease (CLD) are at increased risk of adverse perioperative outcomes. Effective preoperative risk stratification and optimization are critical to minimizing perioperative complications. This article summarizes key aspects of perioperative care in patients with CLD, including pathophysiology, preoperative risk assessment, and evidence-based perioperative care strategies. For patients with hepatocellular carcinoma require liver resection, a multidisciplinary approach is recommended to optimize surgical candidacy and outcomes. In addition, altered bioavailability of opioids and other analgesics necessitates individualized postoperative pain management, emphasizing multimodal approaches tailored to hepatic function. Graphical Abstract

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Journal
Anesthesiology and Perioperative Science
Published
2026-01-06
DOI
https://doi.org/10.1007/s44254-025-00143-0
Primary Topic
Cancer, Stress, Anesthesia, and Immune Response
Type
article
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article

Current updates in perioperative care for patients with chronic liver disease

Mayura Thilanka Iddagoda, Sherman Picardo, Leon Flicker
Anesthesiology and Perioperative Science
Cancer, Stress, Anesthesia, and Immune Response
article

Current updates in perioperative care for patients with chronic liver disease

Mayura Thilanka Iddagoda, Sherman Picardo, Leon Flicker
article en

Abstract

Abstract Patients with chronic liver disease (CLD) are at increased risk of adverse perioperative outcomes. Effective preoperative risk stratification and optimization are critical to minimizing perioperative complications. This article summarizes key aspects of perioperative care in patients with CLD, including pathophysiology, preoperative risk assessment, and evidence-based perioperative care strategies. For patients with hepatocellular carcinoma require liver resection, a multidisciplinary approach is recommended to optimize surgical candidacy and outcomes. In addition, altered bioavailability of opioids and other analgesics necessitates individualized postoperative pain management, emphasizing multimodal approaches tailored to hepatic function. Graphical Abstract

Anesthesiology and Perioperative ScienceVol. 4(1)
The University of Western Australia (AU), Royal Perth Hospital (AU)
Good health and well-being
Openalex Percentile: Top 95%
Cancer, Stress, Anesthesia, and Immune Response
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Current updates in perioperative care for patients with chronic liver disease — Mayura Thilanka Iddagoda, Sherman Picardo, et al. · Anesthesiology and Perioperative Science (2026) | TGRS Research Map | TGRS