Case Report: Massive subcapsular hepatic hematoma after spontaneous rupture of pyogenic liver abscess in a healthy young woman

Bacterial and parasitic agents can cause liver abscess (LA), and spontaneous rupture of a pyogenic liver abscess (PLA) represents an exceedingly rare but life-threatening event. Upon abscess rupture, a sudden influx of pus and bacterial toxins into the peritoneal cavity can trigger a dysregulated host response to infection. Should major intrahepatic vessels be involved, life-threatening hemorrhagic shock may supervene, with clinical deterioration occurring within hours. We present the first case of a young woman with a ruptured liver abscess complicated by a massive subcapsular hematoma who rapidly developed hemorrhagic and septic shock and underwent emergency laparoscopic surgery followed by intensive care unit (ICU) admission. No adverse complications were observed in follow-ups at one, three, and six months after the operation. This case emphasizes that even immunocompetent young adults can experience acute abscess rupture with life-threatening hemorrhagic shock, mandating early recognition, prompt intervention, and multidisciplinary management.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-01-08
DOI
https://doi.org/10.3389/fmed.2025.1713210
Primary Topic
Amoebic Infections and Treatments
Type
article
Field-Weighted Citation Impact
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article

Case Report: Massive subcapsular hepatic hematoma after spontaneous rupture of pyogenic liver abscess in a healthy young woman

J S Chen, Liyong Zhang, Jinhua Cui, ZiYu Bai et al.
Frontiers in Medicine
Amoebic Infections and Treatments
article

Case Report: Massive subcapsular hepatic hematoma after spontaneous rupture of pyogenic liver abscess in a healthy young woman

J S Chen, Liyong Zhang, Jinhua Cui, ZiYu Bai, Aijun Yu, Zejin Zhao, Kai Chen, Jian Li, Kunyu Huang, Zhuqing Zhang
article en

Abstract

Bacterial and parasitic agents can cause liver abscess (LA), and spontaneous rupture of a pyogenic liver abscess (PLA) represents an exceedingly rare but life-threatening event. Upon abscess rupture, a sudden influx of pus and bacterial toxins into the peritoneal cavity can trigger a dysregulated host response to infection. Should major intrahepatic vessels be involved, life-threatening hemorrhagic shock may supervene, with clinical deterioration occurring within hours. We present the first case of a young woman with a ruptured liver abscess complicated by a massive subcapsular hematoma who rapidly developed hemorrhagic and septic shock and underwent emergency laparoscopic surgery followed by intensive care unit (ICU) admission. No adverse complications were observed in follow-ups at one, three, and six months after the operation. This case emphasizes that even immunocompetent young adults can experience acute abscess rupture with life-threatening hemorrhagic shock, mandating early recognition, prompt intervention, and multidisciplinary management.

Frontiers in MedicineVol. 12
Chengde Medical University (CN)
Good health and well-being
Openalex Percentile: Top 98%
Amoebic Infections and Treatments
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