In vivo imaging of the outer retina after an autologous neurosensory retinal free flap transplantation for a refractory macular hole closure

Although the exact physiological mechanisms that promote macular hole closure and intraretinal cellular changes after an autologous neurosensory retinal free flap transplantation are unknown, imaging supports the procedure as a reasonable surgical option for refractory macular hole closure. The preserved integrity of the host tissue suggests that the graft does not negatively impact the retina following the surgery. Furthermore, the improvement in the inner segment/outer segment junction and external limiting membrane noted over time within the graft are considered favorable as they relate to the structure and function of the retina.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2026-01-07
DOI
https://doi.org/10.1186/s13256-025-05751-9
Primary Topic
Retinal and Macular Surgery
Type
article
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article

In vivo imaging of the outer retina after an autologous neurosensory retinal free flap transplantation for a refractory macular hole closure

Matthew Ohr, Nathan Doble, Stacey S. Choi, Danae A. Johnson
Journal of Medical Case Reports
Retinal and Macular Surgery
article

In vivo imaging of the outer retina after an autologous neurosensory retinal free flap transplantation for a refractory macular hole closure

Matthew Ohr, Nathan Doble, Stacey S. Choi, Danae A. Johnson
article en

Abstract

Although the exact physiological mechanisms that promote macular hole closure and intraretinal cellular changes after an autologous neurosensory retinal free flap transplantation are unknown, imaging supports the procedure as a reasonable surgical option for refractory macular hole closure. The preserved integrity of the host tissue suggests that the graft does not negatively impact the retina following the surgery. Furthermore, the improvement in the inner segment/outer segment junction and external limiting membrane noted over time within the graft are considered favorable as they relate to the structure and function of the retina.

Journal of Medical Case ReportsVol. 20(1)
The Ohio State University (US)
Good health and well-being
Openalex Percentile: Top 97%
Retinal and Macular Surgery
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In vivo imaging of the outer retina after an autologous neurosensory retinal free flap transplantation for a refractory macular hole closure — Matthew Ohr, Nathan Doble, et al. · Journal of Medical Case Reports (2026) | TGRS Research Map | TGRS