Antibiotic exposure impairs the efficacy of first-line chemoimmunotherapy in non-small cell lung cancer through the regulation of gut microbiome and bile acid metabolism
Antibiotic exposure is associated with decreased efficacy of chemoimmunotherapy in patients with NSCLC via dysregulation of the gut microbiome and DCA metabolism.
Authors
- Hui Xu (ORCID: https://orcid.org/0000-0001-5517-3556)
- Pengcheng Lin (ORCID: https://orcid.org/0000-0002-0697-0011)
- Shixin Su (ORCID: https://orcid.org/0000-0002-5334-2827)
- Chengshui Chen
- Liwen Zhou
- Jia Yu
- Xiong lei
- Yuping Li
- Lijing Xia
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Quzhou City People's Hospital (CN)
Publication Details
- Journal
- Precision Clinical Medicine
- Published
- 2026-01-06
- DOI
- https://doi.org/10.1093/pcmedi/pbag001
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00