Integrated metabolomics and gut microbiota to reveal the anti-tumor mechanism of Jinfu’an decoction in tumor-bearing mice

JFAD regulates the homeostasis of intestinal flora and influences amino acid and succinic acid metabolism through various pathways. These mechanisms could serve as potential targets for JFAD in inhibiting lung cancer invasion and metastasis.

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Publication Details

Journal
Frontiers in Microbiology
Published
2026-01-06
DOI
https://doi.org/10.3389/fmicb.2025.1643268
Primary Topic
Metabolomics and Mass Spectrometry Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Integrated metabolomics and gut microbiota to reveal the anti-tumor mechanism of Jinfu’an decoction in tumor-bearing mice

H. C. Li, Yantao Li, Zhongming Huang, Huiting Peng et al.
Frontiers in Microbiology
Metabolomics and Mass Spectrometry Studies
article

Integrated metabolomics and gut microbiota to reveal the anti-tumor mechanism of Jinfu’an decoction in tumor-bearing mice

H. C. Li, Yantao Li, Zhongming Huang, Huiting Peng, S. Peter Wu, Shuqiao Zhang, Zhe Sun, Lin Lin, Peiqin Li, Yang Cao
article en

Abstract

JFAD regulates the homeostasis of intestinal flora and influences amino acid and succinic acid metabolism through various pathways. These mechanisms could serve as potential targets for JFAD in inhibiting lung cancer invasion and metastasis.

Frontiers in MicrobiologyVol. 16
Guangzhou University of Chinese Medicine (CN), Longyan University (CN), Shantou University (CN), Cancer Hospital of Shantou University Medical College (CN), First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
Openalex Percentile: Top 97%
Metabolomics and Mass Spectrometry Studies
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