Non‐Steroidal Anti‐Inflammatory Drugs After Abdominal Surgery: An Umbrella Review of Existing Evidence

NSAIDs after abdominal surgery reduce pain, opioid consumption, and the time to gut recovery. In the context of colorectal surgery, non-selective NSAIDs may increase the risk of anastomotic leak, but this is based on low quality data. Their use should be limited to selective NSAIDs until robust evidence is available to guide decision-making.

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Publication Details

Journal
ANZ Journal of Surgery
Published
2026-01-07
DOI
https://doi.org/10.1111/ans.70468
Primary Topic
Enhanced Recovery After Surgery
Type
article
Field-Weighted Citation Impact
0.00

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article

Non‐Steroidal Anti‐Inflammatory Drugs After Abdominal Surgery: An Umbrella Review of Existing Evidence

A. G. Nicholls, Mikolaj R. Kowal, Stephen J. Chapman, David George Jayne
ANZ Journal of Surgery
Enhanced Recovery After Surgery
article

Non‐Steroidal Anti‐Inflammatory Drugs After Abdominal Surgery: An Umbrella Review of Existing Evidence

A. G. Nicholls, Mikolaj R. Kowal, Stephen J. Chapman, David George Jayne
article en

Abstract

NSAIDs after abdominal surgery reduce pain, opioid consumption, and the time to gut recovery. In the context of colorectal surgery, non-selective NSAIDs may increase the risk of anastomotic leak, but this is based on low quality data. Their use should be limited to selective NSAIDs until robust evidence is available to guide decision-making.

ANZ Journal of SurgeryVol. 96(3)
University of Leeds (GB), Royal Hallamshire Hospital (GB)
Bowel Cancer UK, National Institute for Health and Care Research, Department of Health and Social Care, European Commission
Good health and well-being
Openalex Percentile: Top 97%
Enhanced Recovery After Surgery
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Non‐Steroidal Anti‐Inflammatory Drugs After Abdominal Surgery: An Umbrella Review of Existing Evidence — A. G. Nicholls, Mikolaj R. Kowal, et al. · ANZ Journal of Surgery (2026) | TGRS Research Map | TGRS