Association between lymphocyte to high-density lipoprotein ratio and total bone mineral density in 8–19-year-old children and adolescents: a cross-sectional study

In US children and adolescents, a higher LHR is independently associated with lower total BMD, exhibiting an L-shaped curve with a threshold effect at 1.26. These findings suggest that LHR may serve as a useful and accessible biomarker for assessing bone health risk in the young population. Further prospective studies are needed to elucidate the causal mechanisms underlying this association.