Quantifying Disease Activity Despite Treatment with Tumor Necrosis Factor Inhibitors Among Patients with Psoriatic Arthritis and Axial Spondyloarthritis: Real-World Results from the PPD CorEvitas Psoriatic Arthritis/Spondyloarthritis Registry

More than 80% of patients with PsA or axSpA who did not achieve low disease activity at 6 months still did not achieve low disease activity by 12 months even though they persisted on TNFi treatment. These findings underscore the importance for physicians to consider modifying therapy if treatment targets with TNFi have not been achieved in the first 6 months.

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Journal
Rheumatology and Therapy
Published
2026-01-07
DOI
https://doi.org/10.1007/s40744-025-00813-2
Primary Topic
Spondyloarthritis Studies and Treatments
Type
article
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article

Quantifying Disease Activity Despite Treatment with Tumor Necrosis Factor Inhibitors Among Patients with Psoriatic Arthritis and Axial Spondyloarthritis: Real-World Results from the PPD CorEvitas Psoriatic Arthritis/Spondyloarthritis Registry

Melissa Eliot, Taylor Blachley, X. Ye, B. Parikh et al.
Rheumatology and Therapy
Spondyloarthritis Studies and Treatments
article

Quantifying Disease Activity Despite Treatment with Tumor Necrosis Factor Inhibitors Among Patients with Psoriatic Arthritis and Axial Spondyloarthritis: Real-World Results from the PPD CorEvitas Psoriatic Arthritis/Spondyloarthritis Registry

Melissa Eliot, Taylor Blachley, X. Ye, B. Parikh, Christopher D. Saffore, S. Ciecinski, Alexis Ogdie, Nicole Middaugh, Philip Mease
article en

Abstract

More than 80% of patients with PsA or axSpA who did not achieve low disease activity at 6 months still did not achieve low disease activity by 12 months even though they persisted on TNFi treatment. These findings underscore the importance for physicians to consider modifying therapy if treatment targets with TNFi have not been achieved in the first 6 months.

Rheumatology and TherapyVol. 13(2)
AbbVie (United States) (US), Swedish Medical Center (US), Thermo Fisher Scientific (United States) (US), University of Pennsylvania (US)
Good health and well-being
Openalex Percentile: Top 97%
Spondyloarthritis Studies and Treatments
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Quantifying Disease Activity Despite Treatment with Tumor Necrosis Factor Inhibitors Among Patients with Psoriatic Arthritis and Axial Spondyloarthritis: Real-World Results from the PPD CorEvitas Psoriatic Arthritis/Spondyloarthritis Registry — Melissa Eliot, Taylor Blachley, et al. · Rheumatology and Therapy (2026) | TGRS Research Map | TGRS