Increased risk of uveitis and optic neuritis after herpes zoster reactivation in COVID-19: a TriNetX database study

HZ reactivation after COVID-19 is related to a higher instantaneous risk of subsequent uveitis and optic neuritis, even among immunocompetent individuals. HZ may serve as a clinical marker for neuro-immune injury, supporting the consideration of targeted ophthalmic surveillance and timely antiviral intervention to prevent vision loss.

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Publication Details

Journal
QJM
Published
2026-01-02
DOI
https://doi.org/10.1093/qjmed/hcaf332
Citations
4
Primary Topic
Retinal and Optic Conditions
Type
article
Field-Weighted Citation Impact
90.20
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article

Increased risk of uveitis and optic neuritis after herpes zoster reactivation in COVID-19: a TriNetX database study

Man Sze Wong, Yu‐Chen Cheng, Kuo-Cheng Lu, Ai-Ling Hour et al.
4 citations
QJM
Retinal and Optic Conditions
90.20
article

Increased risk of uveitis and optic neuritis after herpes zoster reactivation in COVID-19: a TriNetX database study

Man Sze Wong, Yu‐Chen Cheng, Kuo-Cheng Lu, Ai-Ling Hour, Ming Ling Tsai, Shan-Shy Wen, Chien-Lin Lu, Yi-Hsin Lin
article en
4 citations

Abstract

HZ reactivation after COVID-19 is related to a higher instantaneous risk of subsequent uveitis and optic neuritis, even among immunocompetent individuals. HZ may serve as a clinical marker for neuro-immune injury, supporting the consideration of targeted ophthalmic surveillance and timely antiviral intervention to prevent vision loss.

QJM
Fu Jen Catholic University (TW), Taipei Medical University Hospital (TW), Taipei Tzu Chi Hospital (TW), National Taiwan University Hospital (TW), Buddhist Tzu Chi Medical Foundation (US)
Good health and well-being
Openalex Percentile: Top 0%
Retinal and Optic Conditions
90.20
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Increased risk of uveitis and optic neuritis after herpes zoster reactivation in COVID-19: a TriNetX database study — Man Sze Wong, Yu‐Chen Cheng, et al. · QJM (2026) | TGRS Research Map | TGRS