Antibiogram and characterization of resistance prevalence among Klebsiella pneumoniae isolates

Finding and isolating resistant strains of Klebsiella species and analyzing their antibiogram profiles were the goals of the study, which examined the prevalence of Klebsiella sp. among patients suspected of UTI in hospitals in Al-Bayda, Libya. UTIs are among the most frequent infections, both in the community and in hospitals. We employed API20E to confirm the species-level identification of the selected bacterial isolate, which had previously passed conventional recognition. Twenty-six strains of K. pneumoniae were isolated from urine samples of patients with UTIs. K. pneumoniae was substantially more common in female specimens than in male samples. Seven kinds of antimicrobial medications were used to evaluate the antibiotic resistance profile of these bacteria. Nearly 80% of the K. pneumoniae strains were resistant to at least three of the tested medications. Colistin, polymyxin-B, and piperacillin/tazobactam were the most sensitive antibiotics among the isolates. Resistance to macrolides, amphenicol, and lincosamide was almost equal (20%). The percentages of resistance to aminoglycosides and quinolones were 3.4% and 20%, respectively. The antibiotic resistance to traditional beta-lactams was the highest; however, this resistance was significantly reduced when beta-lactam combinations were tried.