Interstitial Cells of Cajal Remodeling as a Mechanistic Insight Into the Natural History of Achalasia: Lessons From 3 Clinical Cases

We read with great interest recent casebased report in Journal of Neurogastroenterology and Motility describing the dynamic clinical course of achalasia.Taken together from another reports, these cases illustrate not only the progression of esophageal motor dysfunction but also the potential for partial remission, providing a unique window to consider the role of interstitial cells of Cajal (ICC) remodeling in disease evolution.

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Publication Details

Journal
Journal of Neurogastroenterology and Motility
Published
2026-01-06
DOI
https://doi.org/10.5056/jnm25182
Primary Topic
Gastroesophageal reflux and treatments
Type
article
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article

Interstitial Cells of Cajal Remodeling as a Mechanistic Insight Into the Natural History of Achalasia: Lessons From 3 Clinical Cases

Bibo Zhong, Youhong Hu, Anlong Yuan, Jiguang Kou et al.
Journal of Neurogastroenterology and Motility
Gastroesophageal reflux and treatments
article

Interstitial Cells of Cajal Remodeling as a Mechanistic Insight Into the Natural History of Achalasia: Lessons From 3 Clinical Cases

Bibo Zhong, Youhong Hu, Anlong Yuan, Jiguang Kou, Ziwei Li
article en

Abstract

We read with great interest recent casebased report in Journal of Neurogastroenterology and Motility describing the dynamic clinical course of achalasia.Taken together from another reports, these cases illustrate not only the progression of esophageal motor dysfunction but also the potential for partial remission, providing a unique window to consider the role of interstitial cells of Cajal (ICC) remodeling in disease evolution.

Journal of Neurogastroenterology and MotilityVol. 32(1)
The Central Hospital of Xiao gan (CN), Wuhan University of Science and Technology (CN)
Zero hunger
Openalex Percentile: Top 97%
Gastroesophageal reflux and treatments
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