Changes of the cardiac electrical cycle in type 1 diabetes during hypoglycaemia – a prospective observational study

Daytime hypoglycaemia is an unlikely cause of malignant arrhythmias in healthy patients with type 1 diabetes. The minimal increase in the QTc interval alone does not suggest an increased risk of malignant arrhythmias. However, the increase in the mean QTc together with an increase in its SD during nighttime hypoglycaemia is compatible with the extremely rare occurrence of the "dead-in-bed" syndrome.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-01-06
DOI
https://doi.org/10.3389/fendo.2025.1690371
Primary Topic
Diabetes Management and Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Changes of the cardiac electrical cycle in type 1 diabetes during hypoglycaemia – a prospective observational study

Viktor J. Horváth, Viktor Vass, Tamás Jávorfí, Győző Kocsis et al.
Frontiers in Endocrinology
Diabetes Management and Research
article

Changes of the cardiac electrical cycle in type 1 diabetes during hypoglycaemia – a prospective observational study

Viktor J. Horváth, Viktor Vass, Tamás Jávorfí, Győző Kocsis, Márk M. Svébis, Viktória Ferencz, Ádám G. Tabák, Árpád Kézdi, Beatrix A. Domján
article en

Abstract

Daytime hypoglycaemia is an unlikely cause of malignant arrhythmias in healthy patients with type 1 diabetes. The minimal increase in the QTc interval alone does not suggest an increased risk of malignant arrhythmias. However, the increase in the mean QTc together with an increase in its SD during nighttime hypoglycaemia is compatible with the extremely rare occurrence of the "dead-in-bed" syndrome.

Frontiers in EndocrinologyVol. 16
Semmelweis University (HU), The London College (GB), Jahn Ferenc Dél-Pesti Kórház és Rendelőintézet (HU), University College London (GB)
Magyar Diabetes Társaság, Medical Research Council, Nemzeti Kutatási, Fejlesztési és Innovaciós Alap
Good health and well-being
Openalex Percentile: Top 97%
Diabetes Management and Research
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