Bone turnover markers (β-CTX, PINP, ALP) in osteoporosis: correlation with bone loss and fracture risk stratification
Elevated β-CTX, PINP, and ALP levels correlate with reduced BMD and independently predict secondary fracture risk in osteoporosis patients. Integrating these biomarkers with BMD enhances fracture risk stratification, supporting their inclusion in clinical risk assessment tool.
Authors
- Liangming Wang
- Liquan Cai
- Qingfeng Ke
- Xiaolu Zhang
- Jie Xu
- Shiqiang Wu
Institutions
- Fujian Medical University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-01-05
- DOI
- https://doi.org/10.3389/fendo.2025.1628434
- Citations
- 1
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 39.58
Funders
- Fujian Provincial Department of Science and Technology