Identification of epigenetic monotherapy candidates in taxane-resistant CRPC
This study highlights epigenetic vulnerabilities in taxane-resistant CRPC and identifies 4-Iodo-SAHA and SP2509 as promising monotherapy candidates, demonstrating their ability to potentiate Dtx activity and overcome resistance.
Authors
- İpek Bulut (ORCID: https://orcid.org/0000-0001-7267-3632)
- Buse Cevatemre (ORCID: https://orcid.org/0000-0002-0437-6385)
- Ceyda Acilan
- Ezgi Karyemez (ORCID: https://orcid.org/0000-0001-5776-7323)
Institutions
- Koç University (TR)
Publication Details
- Journal
- TURKISH JOURNAL OF BIOLOGY
- Published
- 2025-12-29
- DOI
- https://doi.org/10.55730/1300-0152.2778
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00