Identification of TYR gene variants associated with white coat color in Hanwoo cattle using whole-genome sequencing

This study highlights significant genomic differences between White and Brown Hanwoo populations, including reduced genetic diversity in White Hanwoo due to potential inbreeding. In addition, it confirms the TYR gene as a critical determinant of coat color through the identification of a functionally relevant missense variant. These findings provide valuable insights for Hanwoo breeding and conservation strategies and lay the foundation for further functional studies on pigmentation-related genes.