Tolerability and Feasibility of Minimally Invasive Canine Skin Sampling: Excellent Tolerability Meets Transcriptomic Challenges

Minimally invasive skin sampling methods are feasible and well-tolerated in dogs. Among the techniques evaluated, TS showed the most potential for transcriptomic applications. However, RNA quality remains a key limitation. Further refinement in sample processing and handling is essential to improve consistency and enable reliable downstream analyses in veterinary dermatological research.