Apicobasal Polarity Protein PARD3 Plays an Essential Role in Human Corneal Epithelial Cells
PARD3 regulates human CE cell proliferation, ECM-binding, migration, F-actin polymerization, and barrier function. Loss of PARD3 activity pushes CE cells toward epithelial-mesenchymal transition.
Authors
- Peri Sohnen
- Shivalingappa K. Swamynathan
- Mehak Vohra
- Danielle M. Robertson (ORCID: https://orcid.org/0000-0002-0136-2041)
- Satinder Kaur
- Simran Kumar
- Sudha Swamynathan
Institutions
- University of South Florida (US)
- Southwestern Medical Center (US)
- Dr. Shroff’s Charity Eye Hospital (IN)
- Southwestern Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
- Stanford University (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2026-01-05
- DOI
- https://doi.org/10.1167/iovs.67.1.3
- Primary Topic
- Proteoglycans and glycosaminoglycans research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of South Florida
- National Institutes of Health
- National Eye Institute