Efficacy of dexamethasone intravitreal implant combined with anti-VEGF drugs in the treatment of diabetic macular edema: a systematic review and meta-analysis

DEX combined with anti-VEGF agents confers superior anatomical outcomes in reducing CMT compared to anti-VEGF monotherapy in the management of DME. However, further large-scale, multicenter randomized controlled trials with extended follow-up are warranted to validate these findings and optimize treatment protocols.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-01-05
DOI
https://doi.org/10.3389/fendo.2025.1673371
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy of dexamethasone intravitreal implant combined with anti-VEGF drugs in the treatment of diabetic macular edema: a systematic review and meta-analysis

X Wang, Yiping Xian, Ming Chen, Mei Xin et al.
Frontiers in Endocrinology
Retinal Diseases and Treatments
article

Efficacy of dexamethasone intravitreal implant combined with anti-VEGF drugs in the treatment of diabetic macular edema: a systematic review and meta-analysis

X Wang, Yiping Xian, Ming Chen, Mei Xin, Fang Chen
article en

Abstract

DEX combined with anti-VEGF agents confers superior anatomical outcomes in reducing CMT compared to anti-VEGF monotherapy in the management of DME. However, further large-scale, multicenter randomized controlled trials with extended follow-up are warranted to validate these findings and optimize treatment protocols.

Frontiers in EndocrinologyVol. 16
First Affiliated Hospital of Chengdu Medical College (CN)
Good health and well-being
Openalex Percentile: Top 96%
Retinal Diseases and Treatments
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